I prefer apt/aptitude and the *.debs. It's comfortable, easy to use and allows me to upgrade the whole OS (Debian) with just one command. OpenBSD's packages come next, really smooth and easy to use. That's one of the main reasons why I'm into OpenBSD - almost no compiling at all - exept when running -current
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The only (little!) criticism I have about packages is the missing ncurses-frontend like aptitude.