I use CentOS for work apps I've had problems running in OpenBSD. It works fine, and since it's pretty much mirrored off Red Hat Enterprise, it's got a lot of popularity (which is important if you don't know what you're doing.)
But I would agree with the advice above- for your first couple of years pick a distro and stick with it (unless it seriously disagrees with you.) Too many have bopped around from distro to distro while learning the ropes, only to find themselves utterly confused.
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Network Firefighter
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